Welcome to the N.H.K. is the least Gonzo-type Gonzo show I've seen in a while. I'm fairly satisfied with the ending, and I'm intrigued enough that I may start reading the manga. I understand that the two diverge somewhat in their approaches and plotlines.
I can fully understand how Satou feels about Misaki, but I have to wonder if I would care about what happens to her nearly as much if she wasn't cute. I mean, Misaki is kinda Cocoa Puffs, but she's also curiously angelic. (This is pretty much also how Satou sees her.)
As for Satou, I like how despicable a person he is, but I didn't care much for the show's attempts at humor during which Satou freaks out and grossly overreacts to something. These moments remind me too much of Hideki from Chobits.
Speaking of which, I'm convinced that Chobits would have been a much better show if Hideki had been a hikkimori. Alas, it was ronin that were all the rage back then. Opportunity wasted.